2021 Aprilia Tuono V4

. It is based on the Aprilia RSV Mille.

Although the V2 model remained in production into that year.

The Tuono V4 was offered with Aprilia's APRC (Aprilia Performance Ride Control) system, which included eight-level traction control, three-level wheelie control, and three-level launch control.

Refinements included an enlarged 18.5 L fuel tank, a more comfortable saddle, and a three-level race ABS system. Dyno testing measured output at 153.6 hp (114.5 kW) and 77.1 lb⋅ft (104.5 N⋅m) of torque at the rear wheel.

The Tuono was upgraded with an enlarged 1,077 cc (65.7 cu in) V4 engine. The model was renamed the Tuono V4 1100 RR, with a higher-specification Factory version equipped with Öhlins suspension.

The Tuono V4 1100 was updated with a new TFT instrument display. Aprilia claimed power output of 173–175 hp (129–130 kW) at 11,000 rpm.